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This is very similar to the Red Slime but is bigger. It is red with one eyeball.
It will sludge around to the player, trying to make contact. At the last second, its "face" will extend and bite the player. Handle with caution, as they cut corners to get to the player faster.
- It is one of the two bosses to be a larger version of a previous enemy, the other is the Spider Boss .
- It could be a block of blood from the patients at the hospital or could be waste, like vomit or hazardous chemicals.
- It is unknown how a slime (who has no hands) would carry a gun unless it did so by absorbing it.
- The previous appearance of the Red Slime Boss resembled a Magma Cube from Minecraft, until Mojang, the developer of Minecraft, forced the Pixel Gun Company to change it due to copyright issues.
- It was removed and replaced by the Chainsaw Doctor.